|
KMID : 0191120200350170115
|
|
Journal of Korean Medical Science
2020 Volume.35 No. 17 p.115 ~ p.115
|
|
|
Prevalence and Incidence of Neuromyelitis Optica Spectrum Disorder in Korea: Population Based Study
|
|
Lee Hye-Lim
Kim Jae-Young
Seok Jin-Myoung
Hong Yoon-Ho
Lim Nam-Gu
Shin Ha-Young
Kim Byung-Jo
Hwang Soon-Young
Min Ju-Hong
Kim Byoung-Joon
|
|
|
Abstract
|
|
|
Background: Although neuromyelitis optica spectrum disorder (NMOSD) is known to be a rare disease, its prevalence and incidence have not yet been studied in Korea. We performed a population-based study to examine the prevalence and incidence of NMOSD in Korea using data from the Korean National Health Insurance (NHI) claims database.
Methods: Data from 2013 to 2017 were obtained, with a washout period set as 2013 and 2014. The prevalence and incidence of NMOSD in 2016 and 2017 were calculated using population census data. Subjects were divided into 5 groups at 15-year intervals, depending on the age at which the diagnostic code was entered. The relative risk (RR) for each age group was compared with the oldest (≥ 60 years) age group.
Results: The overall prevalence was estimated to be 3.36 and 3.56 per 100,000 individuals, with an incidence of 0.41 and 0.65 per 100,000 individuals-year in 2016 and 2017, respectively. The mean age was 43.08 (standard deviation, 14.56) years, and the ratio of male to females was 1:4.7. The incidence was higher in female individuals aged between 30 and 59 years (RR, 2.8?3.05; P < 0.05).
Conclusion: Nationwide prevalence of NMOSD in Korea was 3.36 and 3.56/100,000 and its incidence was 0.41 and 0.65/100,000-year in 2016 and 2017 respectively.
|
|
|
KEYWORD
|
|
|
Neuromyelitis Optica Spectrum Disorder, NMOSD, Prevalence, Incidence
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
    
|
|